Blade of the Vampire (2006)

When an ancient bloodthirsty Vampire Vandalis descends on Hollywood it isn't long before he is preying on innocent runaways. They are toys in his game, but in a variation on the myth our Vampire is weaker and more vulnerable than his old school brethren. He is met by another vampire, Selia, who he's known for hundreds of years. She has psychic powers and tells him that he's being hunted and that the hunter has discovered a mythical "blade" with the power to cut their blood sucking eternal lives very short. Former Detective Grant has given up small time police work to pursue his quest, destroying the murderous Vampire Vandalis. He discovered the "Blade" and has been chasing Vandalis from city to city wading through the dearth of corpses and fear left in Vandalis' wake. Grant will finally confront Vandalis while trying to protect Alexis, a hard edged runaway. Vandalis has been preying on Alexis' friends using some of them to lure in others...